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2024 High 10 Improvements | The Scientist Journal®

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The Scientist’s High 10 Improvements contest is again. This yr we took nominations for cutting-edge merchandise launched between January 2023 and July 2024. The outcomes showcased rising developments in fundamental, translational, and scientific analysis, and past.

From fine-tuned updates to brand-new merchandise set to shake up the methods scientists conduct analysis and enhance how clinicians deal with their sufferers, the winner’s circle consists of established firms and new startups. Taking a look at our high merchandise, it’s clear that superior cell sorting and evaluation applied sciences made an enormous splash this yr. Merchandise that present a spatial spin on cell and tissue evaluation, typically with the assistance of synthetic intelligence and machine studying, captured our judges’ consideration. As well as, omics advances, new applied sciences for medical imaging and monitoring, and higher methods to mannequin illness and detect biomarkers took high ranks. Lastly, a educating software educating the following era of scientists rounds out our high improvements checklist.

We’re joyful to announce the brand new applied sciences that our panel of unbiased judges has chosen as this yr’s High 10 Improvements.

REM-I Platform | Deepcell

1

Many applied sciences assist researchers glean insights into mobile phenotypes, however it’s difficult to manually determine delicate mobile morphology variations, and extra so to do it in an unbiased and quantitative method. Deepcell’s REM-I platform for single-cell evaluation, launched in April 2024, gives vital insights into mobile heterogeneity and performance by combining synthetic intelligence (AI)-based know-how and high-throughput imaging.

“REM-I is admittedly the primary platform that brings AI functionality with excessive decision, bias-free, brightfield imaging and bodily motion as a part of sorting into one platform,” defined Maddison Masaeli, Deepcell co-founder and chief government officer. REM-I makes use of superior microfluidics and optics to seize high-resolution brightfield pictures of every cell in a pattern. The platform combines self-supervised studying and morphometrics (pc imaginative and prescient) to gather morphological info and clusters cells in actual time based mostly on biophysical properties.

REM-I permits researchers to quickly view, evaluate, and type morphologically distinct cell populations, capturing cells which will in any other case be missed by way of guide strategies. Scientific bioinformatician Peter van der Spek at Erasmus Medical Middle, who’s on Deepcell’s scientific advisory board, envisions alternatives to enhance pathology analyses based mostly on his expertise utilizing REM-I for a number of translational analysis initiatives, together with investigations into kidney transplant rejection. “We noticed on the morphology degree, cells which have by no means been noticed by our pathologists. That may be very fascinating since you’re beginning to see new shapes, new states of cells which really open up the biology,” he defined. 

In accordance with Masaeli, Deepcell provides completely different pricing fashions for REM-I, which is presently utilized in analysis solely and is commercially obtainable.

MARDIS: This know-how appears to be the brand new era of microscopy as a result of it might picture and characterize single cells based mostly on AI-training of morphology, relatively than counting on human eye-brain characterization.

REM-I platform

REM-I captures high-resolution brightfield pictures and kinds morphologically distinct cell clusters in actual time.

Deepcell

CosmoSort | Meteor Biotech

Most bulk cell sorters take away cells from their spatial context. Meteor Biotech’s CosmoSort cell sorter retains the unique spatial info whereas isolating stained goal cells based mostly on structural and mobile imaging information.

In accordance with Sumin Lee, Meteor Biotech’s chief know-how officer, engineers at Seoul Nationwide College initially developed the CosmoSort know-how based mostly on collaborations with biomedical researchers seeking to higher reply scientific questions. “We thought, what if we may instantly type out the cells from pathology tissues, in order that we are able to deeply analyze these cells?” mentioned Sumin Lee. 

CosmoSort’s spatially-resolved laser activated cell sorting know-how makes use of near-infrared laser pulses to quickly launch focused cells inside slide-mounted specimens. The instrument preserves the collected cells’ pure states and spatial info, whereas sorting them into retrieval vessels. Scientists can then carry out numerous downstream omics analyses with the remoted cells to achieve spatial insights into mobile range and illness pathology. 

Utilizing this innovation, scientists can derive detailed information about a person’s tumor microenvironment. Han-Byoel Lee, a clinician specializing in breast most cancers surgical procedure and analysis at Seoul Nationwide College, was concerned in a number of initiatives assessing tumor tissue utilizing earlier variations of the CosmoSort know-how. In a single research, after isolating areas of curiosity from breast most cancers tissue, “we carried out entire transcriptome and epi-transcriptome analyses on the cells,” mentioned Han-Byoel Lee.1 “We have been in a position to determine adenosine-to-inosine editomes that could be associated to resistance of remedy in triple-negative breast most cancers.”

Meteor Biotech launched its first CosmoSort instrument in March 2024, and their scientists are presently engaged on updating the machine with built-in fluorescence microscopes and AI-driven options.

HOCKBERGER: [The instrument] facilitates transcriptome and epi-transcriptomic insights that make clear mobile capabilities in situ. This know-how is a robust addition to the single-cell multiomics toolbox.

     Meteor Biotech’s CosmoSort spatial cell sorter

CosmoSort kinds cells from smears and tissues whereas sustaining spatial info.

Meteor Biotech


CRISPR in a Field | ChristianaCare® Gene Enhancing Institute

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The leisure business typically misrepresents CRISPR genome enhancing, leaving the general public confused about how this know-how works. Nevertheless, the emergence of gene therapies has sparked pleasure in highschool and faculty college students, inspiring them to be taught extra. Consequently, the ChristianaCare® Gene Enhancing Institute developed the CRISPR in a Field™ instructional equipment and partnered with Carolina® Organic Provide Firm to fabricate and distribute the present model, which they launched in March 2024. 

“[The kit offers] a chance to actually increase the scholars’ understanding by way of hands-on, lively studying,” mentioned Philip Kudish, a science teacher at Delaware Technical Group School, who acquired the equipment for beta testing. “One of many issues that makes CRISPR in a Field so versatile is that the CRISPR gene enhancing step is completed in vitro.” Usually, CRISPR cleavage and gene restore processes happen inside goal cells. Nevertheless, the gene enhancing step in CRISPR in a Field doesn’t require cells, which permits educators with out entry to cell tradition gear to nonetheless carry out this portion of the train with their class. 

“We hope that [CRISPR in a Box] goes to demystify gene enhancing know-how,” mentioned Amanda Hewes, one of many inventors of the equipment and the tutorial program supervisor on the ChristianaCare Gene Enhancing Institute. “[Using this kit], we are able to educate the youthful generations about what CRISPR and gene enhancing may do, whether or not it’s in healthcare, agriculture, or another fields,…and hopefully practice a number of the subsequent era of scientists, lecturers, and professionals which can be going to get into the [gene editing] discipline.”

HOCKBERGER: The equipment consists of print supplies and hands-on workouts for highschool and faculty college students occupied with studying the fundamentals of CRISPR gene enhancing.

A photo depicting the contents of the CRISPR in a Box kit.

The CRISPR in a Field™ equipment guides college students and educators by way of an revolutionary gene enhancing experiment.

Carolina® Organic Provide Firm


Tensor Area Mapping | Q Bio

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Magnetic resonance imaging (MRI) is a staple of medical diagnostics, however its energy has been hampered by information variability and the method’s qualitative nature. In Might 2024, Q Bio Inc. unveiled Tensor Area Mapping (TFM), a brand new MRI know-how that gives quantitative imaging information that’s harmonized throughout devices and operators. TFM represents a “quantum leap ahead,” mentioned Q Bio founder, chief know-how officer, and chief government officer Jeff Kaditz in a assertion. Kaditz additional acknowledged that TFM makes “multi-parametric quantification of tissues reproducible throughout machines, which is essential to [artificial intelligence] in MRI and customized drugs.”

TFM know-how will debut in Q Bio’s Mark I full-body scanner, an instrument below growth as of October 2024 that was particularly designed to make the most of what TFM can accomplish. “Quantified MRIs have been anticipated for over 25 years,” defined Thomas Witzel, vice chairman of imaging at Q Bio, in a press launch. “By modeling your complete imaging course of with out idealizing assumptions concerning the {hardware}, we’re not solely enhancing the standard of MRI information but additionally paving the best way for creating new MRI gear optimized for velocity and affected person consolation.”

Q Bio is presently searching for companions to check and show the capabilities of TFM inside real-world well being techniques. “We stay up for sharing our collaborations with healthcare suppliers and researchers to deliver the advantages of TFM to sufferers around the globe,” mentioned chief working officer Clarissa Shen in a assertion.

MARDIS: The superior capabilities of this new MRI know-how can get rid of variability between completely different MRI devices, making quantitative measures of tissues conducive to machine studying or AI-based enhancements.

A stylized futuristic outline of a human brain.

Tensor Area Mapping (TFM) may also help harmonize MRI information.


UG100 | Ultima Genomics

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DNA sequencing has developed to assist the evaluation of huge portions of genetic materials and the manufacturing of huge quantities of information. Researchers search options for workflow bottlenecks, and one of many first locations they flip to is sequencer know-how.

February 2024 marked the total business launch of Ultima Genomics’ UG100™ high-throughput sequencer, which makes use of cutting-edge know-how to enhance sequencing velocity and effectivity. “We’ve got delivered to market a high-throughput, high-quality sequencer that sequences smaller batches at a lower cost level that another sequencer obtainable,” mentioned Jay Therrien, Ultima Genomics’ chief business officer. The corporate prides itself on the UG100’s skill to cut back prices to 100 USD per genome.

Main researcher institutes globally already use the platform. Cheaper and quicker sequencing helps information era and analysis discovery, enabling info extraction from extra cells, tissue sorts, samples, time factors, and coverings. “The extra that we decrease the worth of producing information, the extra might be completed. We see that take maintain in a wide range of market segments,” Therrien mentioned.

Among the many first adopters of the know-how have been scientists at Macrogen Inc., an organization that produces DNA sequence reads for his or her analysis clients and the general public. Seung-been “Steven” Lee, head of the Know-how Technique Workplace at Macrogen Inc., describes UG100’s cost-effectiveness, automation, and reliability as a recreation changer. The platform makes use of a particular spinning silicon wafer to distribute reagents, which hurries up information assortment and imaging tremendously. “The UG100 can retailer as much as six wafers, that’s six circulate cells, and it routinely begins a brand new run,” Lee mentioned. “The automation has been working very nicely, and it actually improved the effectivity of our pipeline.”

KAMDAR: The Ultima UG100 system provides a platform for precision and low-cost genomic sequencing, providing unparalleled accuracy and velocity to unlock deeper insights into the complexity of life’s code.

     Front and side views of Ultima Genomics’ UG100 genome sequencing platform.

Ultima Genomics’ UG100 high-throughput sequencer provides researchers a speedy, environment friendly, and cost-effective resolution to genome sequencing.

Digital Artistic Associates (DCA)


Microscoop | Syncell

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Scientists more and more flip to microscopy-based spatial biology methods to detect, localize, and map proteins, however high-throughput or unbiased spatial proteomics screening stays restricted by technique decision, sensitivity, and specificity. Syncell’s Microscoop™ brings microscopy-guided proteomic discovery into the automated, large-scale realm.

Microscoop is a brand new spatial biology platform that leverages AI and superior picture processing, exact photolabeling-based biotinylation, and a streptavidin bead pull down assay for mass spectrometry evaluation. It performs automated photolabeling for all fields of view in a pattern and might quickly reveal new proteins at particular subcellular areas, similar to protein aggregates in mind tissue or biomarkers in most cancers samples. “This know-how might be the primary excessive precision spatial protein purification technique,” mentioned Jung-Chi Liao, Syncell’s chief government officer. “You may pull [down] the proteins within the location you are occupied with and determine what they’re in a significantly better, a lot quicker method.”

“What many firms now name spatial proteomics is usually candidate-based…Right here the know-how is sort of completely different, as a result of on this case, it is actually discovery-based,” mentioned neurobiologist Wilfried Rossoll from Mayo Clinic, who acquired early entry to the Microscoop system as a winner of Syncell’s Spatial Proteomics Grant Alternative Award. Rossoll’s analysis workforce employed the platform to research key neurodegenerative illness markers inside pathological protein aggregates in human post-mortem mind tissue.

Rossoll additionally led the initiative to deliver a mass spectrometry core facility to the Mayo Clinic in Florida, the place one of many first Microscoop techniques has been put in within the US. The official launch of the Microscoop system coincides with the 2024 American Society for Cell Biology assembly, a consultant for Syncell mentioned through e mail.

MEAGHER: This can be a cool strategy to sub-cellular spatial proteomics that mixes automated microscopy and focused photolabeling to enabled unbiased proteomics of chosen sub-cellular options.

     Microscoop instrument

Syncell’s Microscoop permits automated microscopy-guided proteomic discovery.

syncell


STARVUE | Vizgen (Ultivue)

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When performing spatial picture analyses of heterogeneous tissues, the quantity of information generated can grow to be unmanageable. “If you wish to research, as an illustration, the tumor microenvironment, you could perceive what completely different cell sorts are in your tissue, what is the precise battle ongoing there between the immune system and most cancers cells,” mentioned Lorenz Rognoni, the spatial picture evaluation portfolio proprietor at Vizgen (Ultivue). “In case you then multiplex, you need to overcome this huge information problem.”

To facilitate the exploration of advanced tissues, Vizgen provides a spread of VUE multiplex immunofluorescence (mIF) biomarker panels, which generate wealthy mIF pictures of stained slides. In April 2024, the corporate rolled out the STARVUE™ Picture Information Science Platform to deal with this plethora of information. 

STARVUE makes use of pre-trained, tissue-based picture evaluation purposes to investigate mIF pictures of entire stained slides, offering tissue detection, segmentation, and cell-biomarker classification based mostly on morphology and stain alerts. The cloud-based, automated platform can stack entire slide mIF and same-section hematoxylin and eosin (H&E) stain pictures, and its deep studying fashions classify cells all through advanced and variable tissues with the assistance of synthetic intelligence. 

Scott Daigle, senior director of Translational Drugs at Nimbus Therapeutics, highlighted how scientists at his firm leverage the VUE panels and STARVUE to determine oncology targets that modulate the immune system. “We are able to get majority of our solutions simply from this one assay…Are these T cells participating with the most cancers cells, are they activated, are they doing as we anticipated?” mentioned Daigle. “Tissues from scientific samples are extraordinarily treasured, and so to have the ability to multiplex and get that kind of information is nice.”

KAMDAR: STARVUE empowers researchers with high-definition spatial biology, delivering unprecedented readability and multiplexing capabilities to unravel advanced tissue biology with ease and precision.

Image representing how the STARVUE program analyzes stained tissue

The STARVUE platform gives an in depth look into the advanced tumor microenvironment.

vizgen


Direct RNA Sequencing | Oxford Nanopore Applied sciences

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Transcriptomic evaluation is crucial for characterizing cells in well being and illness. However most RNA sequencing methods don’t instantly analyze native RNA molecules and as a substitute sequence cDNAs. The reverse transcription course of loses important details about the RNA molecules together with base modifications.

To beat this limitation, Oxford Nanopore Applied sciences developed a direct RNA sequencing workflow, which requires a MinION™ nanopore sequencing gadget, a MinION RNA Circulate Cell, and a Direct RNA Sequencing Equipment. This technique permits researchers to comprehensively look at an RNA molecule’s sequence and detect a number of post-translational modifications together with N6-methyladenosine, pseudouridine, inosine, and 5-methylcytosine. 

Oxford Nanopore launched the most recent model of the circulate cell and sequencing equipment, often known as RNA004, in March 2023. “What we have now completed with RNA004 over outdated variations is improved its accuracy, improved its output, and decreased the enter materials requirement,” mentioned Lakmal Jayasinghe, the senior vice chairman of R&D Biologics at Oxford Nanopore.

Moreover, the up to date direct RNA sequencing system can now analyze brief RNAs which can be 50 nucleotides or longer. “The flexibility to learn RNA molecules which can be in any other case very exhausting to [read including] non-coding RNA, structured ribosomal RNA, or tRNA…is exceptional and fairly empowering,” mentioned Miten Jain, a nanopore sequencing skilled at Northeastern College, who acquired the system for beta testing. “[With direct RNA sequencing], we are able to begin taking a look at most cancers cells, neurodegeneration, or pancreatic metabolism-associated fashions and get a greater and extra full image of the panorama of RNA, not simply expression, but additionally modifications.”

MEAGHER: I’m excited to see the know-how mature as a result of I feel this may open new utility areas that may’t be addressed by conventional RNA-seq strategies that begin by reverse-transcribing RNA to cDNA previous to sequencing. 

A photo of a scientist loading their prepared library into a flow cell docked within the MinION device.

The direct RNA sequencing workflow permits researchers to evaluate RNA base modifications in actual time.

Oxford Nanopore Applied sciences


Proteograph XT Assay Equipment | Seer

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Biotech firm Seer launched the Proteograph™ Product Suite in January 2022, giving researchers a technique to research unknown and low-abundance proteins. Nevertheless, they quickly acquired requests for extra throughput and much more depth from scientists seeking to push the envelope, recalled David Horn, chief monetary officer for Seer. The Proteograph XT Assay Equipment, launched in June 2023, is Seer’s reply. “The unique product may course of 16 samples per eight-hour run,” defined Horn. “With the XT, now you are able to do as much as 80. This enables for large-scale research, which we have now seen rising curiosity in.” Horn mentioned that this improved throughput permits research taking a look at as much as 50,000 samples, and he believes that these large-scale research will allow a greater understanding of biology. 

Biochemist Joshua Coon has seen this first-hand. When the COVID-19 pandemic began in spring 2020, Coon and his workforce carried out proteomic analyses on plasma samples. “This was earlier than the Proteograph, and we have been ready detect about 300-350 proteins per pattern.” Since then, the undertaking has moved to learning lengthy COVID: “This summer season, with the Proteograph, we are actually getting 6,500–7,000 proteins per pattern. We’re additionally getting each the markers that we noticed within the first research and new markers which have clear associations. We might be able to separate markers for lengthy COVID from markers for acute COVID, so I’m tremendous excited,” mentioned Coon.

MEAGHER:This can be a intelligent strategy to deal with issues of bias and dynamic vary in proteomics, through the use of completely different units of nanoparticles to selectively pattern for various representations of the proteome, and thereby achieve higher depth of protection of the proteome.

Seer’s Proteograph XT Assay Kit

The Proteograph XT Assay Equipment permits larger throughputs for larger-scale proteomic research.

Seer, Inc


PhysioMimix® Single-Organ Greater Throughput (HT) System | CN Bio

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Precisely reproducing the distinctive microphysiology of human organs in tradition is a prerequisite for producing dependable preclinical information that mimics human physiology and improves translatability. That is very true for scientists engaged in drug discovery and growth analysis.

Launched in February 2023, CN Bio’s PhysioMimix® Single-Organ Greater Throughput (HT) System is a perfused, organ-on-a-chip platform that addresses the necessity for large-scale research to generate sturdy, human related, predictive, and cost-effective preclinical information. “This technique has a complete capability of 144 chips, which might be run concurrently,” mentioned Paul Brooks, chief government officer of CN Bio. That is notably helpful for toxicology and efficacy research, the place knowledgeable choices about information sufficiency mitigate drug failure in future scientific trials. Brooks highlighted configurability as one of many platform’s key benefits. 

The platform bridges conventional cell tradition and the complexity of animal research, permitting researchers to attenuate the variety of animal fashions whereas utilizing a human cell-based system that continues to be devoted to the physiology of human tissues and organs. Alysha Bray, a scientist at CN Bio, believes that this know-how, plus their Liver-48 plate for 3D tradition, simplifies using organ-on-a-chip approaches in laboratories, rising analysis capability and throughput and lowering prices through the use of fewer major cells. “Regardless of the smaller dimension of [each] nicely and tissue, we don’t must compromise on high quality of the info produced,” Bray mentioned. “Utilizing the Liver-48 plate is easy, and the actual fact you need to use a multi-channel pipette for altering media and taking samples is an actual time saver. Each second counts within the lab, and this higher-throughput system permits us to do extra while utilizing much less.”

HOCKBERGER: CN Bio’s new higher-throughput organ-on-a-chip know-how is poised to revolutionize drug discovery, toxicology, and modeling of therapies for human liver ailments.

PhysioMimix® Single-Organ Higher Throughput (HT) System

PhysioMimix® Single-Organ Greater Throughput (HT) System helps researchers create predictive human organ fashions for preclinical testing.

CN Bio

REMI™ Distant EEG Monitoring System | Epitel™

The seizure dysfunction epilepsy impacts roughly 3.4 million folks within the US. Past epilepsy, one in 10 folks could have a seizure of their lifetime, underscoring the significance of seizure detection. Nevertheless, entry to neurologists and electroencephalogram (EEG) screens that file mind exercise stays a niche within the healthcare system. “Right now you might stroll into your neighborhood clinic and stroll out with a wi-fi halter monitor on your coronary heart, however your possibilities of getting an EEG are slim to none. In truth, three quarters of all clinics lack the power to get an EEG,” mentioned Epitel™ chief government officer and chief know-how officer Mark Lehmkuhle.

Epitel’s REMI™ is the primary wi-fi wearable EEG system, enhancing epilepsy administration by way of superior distant monitoring. It permits healthcare professionals to trace seizure exercise in actual time and outdoors of the clinic. The system consists of 4 adhesive sensors that comprise conductive hydrogel, which wirelessly transmit alerts to a devoted smartphone. Machine studying analyzes information saved within the cloud and sends readouts to healthcare suppliers, making it simpler to determine and monitor seizure exercise. REMI is FDA-cleared for dwelling use for as much as 30 days by prescription. 

“Entry to neurology and neurologists is proscribed and might be regularly restricted sooner or later. Know-how like this may also help bridge that hole and make it so there’s larger entry,” mentioned neurologist Steven Benedict at Northern Ohio Medical Specialists, who first used REMI in a scientific outpatient setting throughout beta testing. “Simply having entry, for the sufferers and for the suppliers, and with the ability to reply scientific questions simply, is an amazing profit.”

KAMDAR: Epitel’s REMI revolutionizes distant EEG monitoring, providing real-time, accessible insights into mind exercise that empower clinicians to make quicker, extra knowledgeable choices for higher affected person outcomes.

     REMI sensors

The REMI system’s adhesive sensors wirelessly transmit alerts to a devoted smartphone.

epitel


VisionSort | ThinkCyte

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Launched in the summertime of 2023, ThinkCyte’s VisionSort™ provides superior optics, microfluidics, high-resolution morphological profiling, and AI to standard cytometry. 

Conventional circulate cytometry requires fluorescent labels, which may alter cells’ native states and can’t seize cell morphology at excessive decision. VisionSort is a multi-laser circulate cytometer that makes use of Ghost Cytometry® know-how, a mobile fingerprinting technique that mixes morphological profiling, fluorescence, and AI to outline and type cell populations label-free. With this instrument, researchers can isolate particular cell populations with excessive viability utilizing mild microfluidics, display screen for brand spanking new medicine, and determine novel cell populations in illness. 

Since its launch, researchers have used VisionSort for cell remedy growth, drug discovery, and illness profiling. “Whether or not it’s isolating really untouched and phenotypically outlined cells, performing CRISPR-based phenotypic screens by circulate cytometry, or figuring out novel cell populations in illness, VisionSort provides researchers the power to do issues they couldn’t do earlier than,” mentioned Willem Westra, vice chairman of Enterprise Growth and Advertising at Thinkcyte, in an e mail.

Scientists at VCCT Inc., a regenerative drugs firm that develops cell therapies for retinal degeneration, started utilizing VisionSort in early 2024. “A vital ingredient of our analysis and growth pipeline requires evaluation of induced pluripotent stem cell-derived retinal cells, a longstanding problem as a result of lack of particular floor markers, reporters, or chemical labels,” mentioned Masayo Takahashi, president of VCCT Inc., in an e mail. “This strategy permits our researchers to complement reside, phenotypically-defined cells and use them in downstream steps.”

MARDIS: This know-how {couples} the innovation of AI-driven cell sorting that’s educated on 3D morphology to determine cells, coupled with typical cell surface-labeling utilizing fluorescent antibodies.

     ThinkCyte’s VisionSort multi-laser flow cytometer

VisionSort combines superior optics, microfluidics, and AI to type cells.

ThinkCyte Inc.


THE JUDGES

     Neuroscientist Philip Hockberger

Philip Hockberger

Philip Hockberger is internationally acknowledged for his management position in shared analysis services and for his efforts to create a brand new profession path for core scientists. He’s a member of the Govt Board of BioImaging, North America and the Nationwide Science Basis’s Nationwide Visiting Committee. He was a professor of neuroscience at Northwestern College for 36 years. He has been co-chair of Euro-BioImaging and a member of the Federation of American Societies for Experimental Biology’s Activity Power on Shared Analysis Assets.


     Venture capitalist Kim Kamdar

Kim Kamdar

Kim Kamdar is a managing accomplice at Medical Excellence Capital, a healthcare-focused enterprise fund creating and investing in biopharmaceutical and diagnostic firms. She started her profession as a scientist and pursued drug discovery analysis at Novartis/Syngenta for 9 years.


     Cancer researcher Elaine Mardis

Elaine Mardis

Elaine Mardis is the co-executive director of the Steve and Cindy Rasmussen Institute for Genomic Drugs at Nationwide Kids’s Hospital. She holds the Rasmussen Nationwide Basis Endowed Chair in Genomic Drugs and is a professor of pediatrics at The Ohio State College School of Drugs. Mardis is an skilled in most cancers genomics and immunogenomics, concerned within the scientific profiling of pediatric most cancers DNA and RNA to determine somatic and germline contributors to most cancers onset and to characterize the tumor immune microenvironment.  


     Chemical engineer Robert Meagher

Robert Meagher

Robert Meagher is a chemical engineer by coaching. His analysis pursuits embody microfluidics, bioanalytical chemistry, and molecular diagnostics for infectious illness. He’s the supervisor of the Methods Biology Division at Sandia Nationwide Laboratories, which performs basic analysis in subjects together with microbiology, virology, rising infectious illness, biodefense, and bioenergy.

The statements expressed symbolize the private views of Robert Meagher and don’t mirror the place of Sandia Nationwide Laboratories, Nationwide Know-how & Engineering Options of Sandia, LLC, the Nationwide Nuclear Safety Administration or the Division of Vitality.


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