Welcome to Ben Greenfield’s Weekly Roundup!
On this weekly put up, I share with you my most attention-grabbing discoveries of the week, together with the newest information on the fronts of health, diet, well being, wellness, biohacking, and anti-aging analysis. I additionally recap my upcoming occasions and particular bulletins so you’ll be able to sustain with alternatives to study, giveaways, reductions, and extra!
New Discoveries
Really feel “Bizarre” Throughout NAD IV Remedy? *These* 3 Suggestions From a Regenerative Medication Pioneer Make Your Therapy Smoother, Quicker & Extra Efficient ⚡
For those who’ve spent any time round longevity clinics, restoration facilities, or high-performance circles recently, you have most likely seen individuals hooked as much as an NAD IV.
NAD (nicotinamide adenine dinucleotide) is among the most vital molecules within the physique for turning meals into vitality and powering mobile restore, which is why these infusions are used to spice up vitality manufacturing, psychological readability, restoration, mitochondrial well being, wholesome ageing, and even resilience after journey, stress, or overtraining.
The factor about NAD infusions is that they’ll really feel intense. Some individuals expertise nausea, flushing, chest strain, restlessness, or an odd “one thing feels off” sensation through the drip. It is why some who attempt it by no means return.
Happily, there are methods to make the method a lot smoother, together with these methods from regenerative medication pioneer (and this Saturday’s podcast visitor), Dr. Joseph Purita.
1. Take TMG Earlier than Your Infusion
TMG (trimethylglycine), also called betaine, acts as a methyl donor. Throughout NAD infusions, your physique produces nicotinamide (NAM), which should be cleared effectively by means of methylation by an enzyme referred to as NNMT (nicotinamide N-methyltransferase). This course of consumes methyl teams and may quickly elevate homocysteine, which indicators that methylation pathways have gotten depleted, decreasing the physique’s means to clear nicotinamide effectively and contributing to uncomfortable side effects. Taking TMG beforehand could assist assist methylation pathways and enhance tolerance.
2. Sip Espresso Throughout The IV
This one surprises individuals. The caffeine in espresso can doubtlessly upregulate NMNAT2 (nicotinamide mononucleotide adenylyltransferase 2), a key enzyme concerned in recycling NAD precursors again into usable NAD+. Caffeine additionally blocks adenosine receptors, which can assist scale back a number of the sluggish or uncomfortable sensations individuals expertise throughout infusions.
3. Use Purple Gentle To Photoactivate The NAD
One other superior technique Dr. Purita makes use of at PUR-FORM is exposing the NAD answer to crimson gentle earlier than it enters the IV bag. This could enhance manufacturing of NADH, the diminished type of NAD, which may then be quickly recycled again into NAD+ by means of mitochondrial complicated I to assist mobile vitality manufacturing.
My take is that NAD IVs generally is a incredible software, however the supply course of makes an enormous distinction within the outcomes.
For those who’ve struggled with uncomfortable side effects or need to get extra from the expertise, these three easy tweaks may make all of the distinction.
If you wish to go deeper on NAD, superior therapies like IVs, and different regenerative medication protocols, you’ll be able to try the sources beneath (and do not forget to tune into Saturday’s present with Dr. Purita by subscribing to my podcast on Spotify, Apple Podcasts, or YouTube):
- The whole lot You Want To Know About NAD+: The Essential Function It Performs In Your Mitochondrial Well being, How NAD+ Slows Down Growing older & Will increase Vitality, Methods To Enhance NAD+ Utilizing Way of life, Why NAD+ Precursors Could Be Problematic & A Protected, Value-Efficient Oral NAD+ Complement Technique.
- The NAD Supersode: All Ben’s Loopy Questions About NAD, Pure Methods To Enhance NAD, Dwelling To 120 With NAD & A lot Extra With Matt Titlow & Michael Roberts.
- Might NAD IVs Be Unhealthy For You (& How To Enhance NAD Naturally), With Dr. Nichola Conlon.
- The AMAZING Future Of Regenerative Medication, The New Sexier Different To Stem Cells, The place You Ought to Get Peptides (& The Finest Peptides Stacks) & Extra With Dr. Matt Prepare dinner.
- Peptides, Biologics & Small Molecules You’ve *By no means Heard Of* For Sleep, Mitochondria, Kidney Well being & Extra, With Jim LaValle.
- Ben Greenfield’s Sport-Altering Biohacks & Well being Developments of 2025: 10 Science-Backed Methods For Revolutionizing Human Efficiency.
- ONE Tiny Blood Spot = HUNDREDS (!) Of Biomarkers, Age & Illness Prediction With Dr. Matt Dawson.
Your 2026 Mom’s Day Reward Information Has Arrived! I Hand-Picked These Presents for Your Mother (+ Laser Lights & EXOSOMES?!) 🩷
Panicking over what to get Mother this Mom’s Day and do not know the place to start out, or simply don’t need to give her one other *boring* present this yr?
Skip the standard suspects: flowers that fade inside three days, candles that shortly burn out, and bathtub bombs that stain your bathtub cotton sweet blue.
The particular girl in your life deserves one thing unimaginable that *really* lasts. I imply, she modified your diapers, proper?
So… I put collectively my 2026 Mom’s Day Reward Information with one factor in thoughts: serving to you give Mother a vetted current that delivers her recent vitality, higher restoration, unparalleled sleep, and long-term well being.
🎁 Only a few highlights from the information:
- Sunlighten mPulse Sauna: Personalised infrared sauna periods for restoration, leisure, detox, and deeper sleep.
- Apollo Neuro: A wearable designed to assist calm, stress resilience, and higher sleep.
- Younger Goose Reward Units: Superior skincare protocols centered on restore, mobile vitality, and pores and skin longevity.
- Pendulum Metabolic Day by day: Clinically studied probiotics for intestine well being, metabolism, and regular vitality.
- LIFEprint HTMA Take a look at: At-home testing to show hidden mineral imbalances, stress patterns, and vitality roadblocks.
- Boundless: My bestselling well being optimization e book filled with methods for hormones, metabolism, longevity, and peak efficiency.
So, what are you ready for?
Scroll by means of, discover Mother a memorable present, and use the low cost codes listed within the information for further financial savings on these time-sensitive offers.
👉 Seize the Excellent Reward for Mother
This Week in Well being & Efficiency: What the Newest Analysis Says
💪⏳ Fasting & Muscle Loss—Not So Quick: Sure, fasting can contribute to muscle loss, however analysis exhibits resistance coaching dramatically improves your means to protect lean mass, even on fasting days. The lesson: when you quick, elevate (learn the examine).
🌙📉 Easy Meal Timing for Higher Metabolic Well being: For those who wrestle with blood sugar swings, cussed physique fats, low HRV, or elevated resting coronary heart fee, one of many easiest interventions could also be avoiding meals for roughly 3 hours earlier than mattress and delaying your first meal for a number of hours after waking. Circadian-aligned consuming continues to indicate highly effective advantages (full examine right here).
🐟🧠 What Is “Sardinemaxxing”?: The web’s newest diet development focuses on consuming extra sardines for his or her wealthy provide of omega-3s, protein, calcium, selenium, and low-mercury comfort. Odd title, however nonetheless a sensible meals (learn extra).
🏆💉 The “Enhanced Video games” Debate Heats Up: A provocative new tackle the drug-permitted “Enhanced Video games” raises questions on ethics, athlete well being, and the place the way forward for elite sport could also be heading. Whether or not you see progress or insanity, it’s price paying consideration (get the total story).
Key Takeaway: This week’s analysis factors to a well-known reality: fundamentals nonetheless win. Elevate weights when you quick, align meals with circadian rhythms, eat nutrient-dense complete meals, and be cautious at any time when shortcuts promise superhuman efficiency.
Need to dive deeper? Click on the hyperlinks above to discover the analysis, and click on right here to comply with me on X for all the newest well being and efficiency information sizzling off the press! 
Product Of The Week
::: Take in Your Food plan’s Vitamins Higher With BIOptimizers MassZymes (& Save 15%) :::
You’ve heard, “You’re what you eat…”
However the true reality is that you’re what you soak up, and even the cleanest, most nutrient-dense eating regimen can fall brief in case your digestion is not optimized.
Enzyme manufacturing naturally declines with age, stress, journey, and laborious coaching, which implies you might be extracting far much less diet out of your meals than you suppose, impacting your restoration, vitality, muscle constructing, and total efficiency.
That is the place BIOptimizers MassZymes is available in.
It is a full-spectrum digestive enzyme system containing 322,000 HUTs of protease, the highest-potency enzyme that helps break down protein into usable amino acids.
Higher digestion means improved nutrient uptake, much less bloating, quicker restoration, and extra return from each chew you eat.
Prepared to really use what you eat?
You may snag 15% off MassZymes with code BEN15 at checkout right here.
Podcasts I Recorded This Week:
Might NAD IVs Be Unhealthy For You (& How To Enhance NAD Naturally), With Dr. Nichola Conlon
How To Be A Higher, Extra Current Father (& Not Get DAD-BOD!) with John Schott
The Newest Content material I Was Featured On This Week:
My Article Feed:
My full article feed and all archives of my articles are right here.
Upcoming Occasions:
ECO26 | Could 14–16, 2026
Healthcare practitioners trying to obtain exponential scientific outcomes by means of Foundational Medication: I am talking at ECO26 (Could 14–16, 2026, in Boise, ID), a three-day occasion that includes cutting-edge training, highly effective networking, and actionable methods to raise your apply (with as much as 20 CEUs obtainable for some practitioner sorts). I will be presenting “The Detox Frontier: Classes from The Edges of Biohacking to On a regular basis Vitality” on Could fifteenth alongside a number of the high minds in practical and foundational medication. You may use this hyperlink to register and declare a $400 low cost!
Final Males Over 40 Well being Summit | June 8–14, 2026
For those who’re a person over 40 trying to enhance your energy, vitality, well being, hormones, restoration, longevity, and efficiency, I am talking on the Final Males Over 40 Well being Summit (June 8–14, 2026), a free 7-day digital occasion that includes 100+ consultants throughout 7 core pillars. I will be presenting “Optimizing the Human Machine for 40 and Past” alongside a number of the finest minds in males’s well being at present. You may register at no cost right here now!
Well being Optimisation Summit | September 11–13, 2026
I am talking on the Well being Optimisation Summit in London (September 11–13, 2026) on the Enterprise Design Centre. This is not your common well being convention. HOS unites the very best minds in biohacking, longevity, diet, health, and medication, with one purpose: to really make individuals more healthy. With 35+ world-class audio system, 120+ cutting-edge manufacturers, and 4,000 like-minded individuals all below one roof, it is two days that would genuinely change the way you method your well being. Get your ticket right here and use code BEN to save lots of 10% off registration!
Eudēmonia | November 5–8, 2026
I am talking at Eudēmonia (November 5–8, 2026, in West Palm Seaside, FL), a prevention-focused, science-based well being, well-being, and longevity summit designed so as to add years to your life and life to your years. Throughout 3 days and 15 venues, you may expertise 200+ talks from 120+ consultants, 300 therapies, and 160+ manufacturers masking every little thing from biohacking, longevity, and hormonal well being to intestine well being, mind well being, peptides, mobility, and extra. I will be main a chat and a motion session alongside a number of the brightest minds in well being at present. Use code BGREENFIELD-EUD-100 for $100 off while you register right here!
The Boundless {Couples} Retreat | November 10–14, 2026
Able to reconnect and recharge along with your associate in paradise? Be part of the Greenfields on the gorgeous Prana Maya resort in Belize for the Boundless {Couples} Retreat, November 10–14, 2026. It is a five-day, all-inclusive escape designed to deepen your relationship, restore your vitality, and create recollections that final a lifetime. From leisure and journey to intimate relationship teaching with Jessa and me, each element is crafted to ship you house with a stronger bond and a reinvigorated spirit. Spots are restricted, so uncover extra and safe yours right here at present!
Keep tuned for future updates—and you may at all times sustain with my LIVE appearances by testing bengreenfieldlife.com/calendar!
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Cheers,
Ben
