Know-how Spotlight| Article
Slicing-edge microfluidics permits full automation of NGS protocols.
Subsequent-generation sequencing (NGS) is an exquisitely delicate method for bulk parallel sequencing of genetic materials. The velocity and total effectivity of NGS workflows allow high-throughput processing and value discount. Pattern preparation is essential for reaching dependable and reproducible downstream extraction outcomes. Consequently, researchers should take nice care throughout this essential step, which may typically be sophisticated and cumbersome.1

INTEGRA Biosciences’ MIRO CANVAS microfluidics platform eases the challenges of handbook pattern preparation for next-generation sequencing.
Integra
The power to navigate the challenges of handbook NGS pattern preparation could make or break an experiment. For instance, making ready NGS libraries, performing hybridizations, and following protocols for pattern processing, goal enrichment and long-read sequencing typically requires troubleshooting that may additional delay experiments and confound outcomes. There are numerous steps concerned, together with mixing, operating the PCR and cleansing up beads, and the general course of is labor and useful resource intensive, growing the possibilities of human error. Researchers search alternate options to handbook NGS pattern preparation that may simplify workflows, save time, decrease reagent use, cut back prices, and enhance experimental flexibility. Automated gadgets are recreation changers, and are more and more turning into laboratory tools staples.
INTEGRA Biosciences’ MIRO CANVAS instrument is a small footprint digital microfluidics platform that gives researchers with an reasonably priced, mild, and fully automated pattern preparation resolution. It additionally minimizes reagent use, as all liquid dealing with is achieved utilizing one disposable cartridge. The MIRO CANVAS transforms time-consuming, multi-step, error-prone handbook pattern preparation into a totally automated, easy course of. The instrument considerably reduces hands-on time to a number of minutes, releasing up scientists to interact in different duties.
Study extra about gadgets for NGS pattern preparation.
What’s the greatest problem you encounter when making ready NGS samples?